Production Technician Lead
5 days ago
About This Opportunity
Fujifilm Diosynth Biotechnologies is growing its locations, capabilities, and teams while looking for passionate, mission-driven people like you who want to make a real difference in people's lives.
As a Manufacturing Technician I, you will work directly with a range of technologies, including single-use cell culture vessels and bacterial fermentation culture vessels.
Key Responsibilities
Upstream Unit:
- Operate Single-Use Cell Culture Vessels/Bioreactors up to 2000L
- Manage Bacterial Fermentation Culture Vessels up to 2000L
- Maintain Alpha Wasserman Continuous Flow Centrifuges
- Handle Disposable Magnetic Mixing Bags and Totes
- Conduct Cell Expansion and Propagation
- Perform Banking/Cryopreservation of Cell Lines and Viruses
- Work with Hyperstack, Cellstack, and other Adherent Cell Technologies
- Carry out Plate counting, microscopic examination
- Monitor cultures, take samples, turn-around of bioreactor and fermenters, sterilization, and inoculation
Downstream Unit:
- Implement Medium to Large-scale filtration systems including Tangential Flow Filtration (TFF)
- Operate Hollow Fiber Tangential Flow Filtration (HFTFF), Nanofiltration, and depth filtration
- Operate Medium to Large-scale Chromatographic systems (ÄKTA)
- Maintain Pre-Packed Columns from 1L to 100L
- Operate Single use mixing systems (Pall & GE)
- Maintain Single Use connectivity types such as GE DAC and Colder AseptiQuik
- Perform Bulk filling
- Carry out Aseptic process simulation and drug product filling
- Carry out Plate counting, microscopic examination
- Monitor cultures, take samples, turn-around of bioreactor and fermenters, sterilization, and inoculation
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